Ex Parte Childers et al - Page 3



               Appeal No. 2003-0890                                                                          Page 3                   
               Application No. 09/706,683                                                                                             






                       The references relied upon by the examiner are:                                                                
               Abou-Gharbia et al. (Abou-Gharbia)                     5,254,552               Oct. 19, 1993                           
               Cliffe                                                 5,420,278               May 30, 1995                            
                       Claims 1, 2, 16, and 27 through 30 stand rejected under 35 U.S.C. § 112, first                                 
               paragraph (enablement).  Claims 1 through 3 stand rejected under 35 U.S.C. § 103(a).                                   
               As evidence of obviousness, the examiner relies upon Abou-Gharbia and Cliffe.  We                                      
               reverse the enablement rejection and affirm the obviousness rejection.                                                 
                                                           Background                                                                 
                       As seen from claims 1 and 16, the claimed invention is directed to a family of                                 
               compounds having a specified formula and their use in treating stroke victims.  The                                    
               claimed compounds are stated to have activity as serotonin 5-HT1A agonists, partial                                    
               agonists and antagonists.  Specification, page 3.                                                                      
                       In regard to making the compounds set forth in claim 1 on appeal, appellants                                   
               state "[t]he compound of formula I can be prepared by conventional chemical methods                                    
               which are well known to those skilled in the art of chemistry using chemicals that are                                 
               either commercially available or readily prepared following standard literature                                        
               procedures."  Specification, page 8.                                                                                   










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