Ex Parte MC NEIL et al - Page 5



                Appeal No.  2003-1017                                                                                 Page 5                    
                Application No. 08/287,358                                                                                                      
                fiber-optic light sources and detectors dedicated to illuminating and detecting individual                                      
                wells” (id.).  Finally, appellants argue that Akong “fails to teach or suggest displaying a                                     
                graphical representation indicating the arrangement in the plate of a plurality of wells”                                       
                (id., page 33).                                                                                                                 
                         In response, the examiner offers several irrelevant arguments.  First, that                                            
                “[Akong’s] apparatus can align one or more different wells to be assayed . . . [which]                                          
                would then encompass exciting and reading any number of wells in a given plate”                                                 
                (Answer, page 10); that “the teachings of Akong would inherently configure exciting and                                         
                reading wells irrespective of their arrangements” (id., page 11); and finally, that “the                                        
                data obtained from the apparatus of Akong is generally charted as a curve and may be                                            
                charted in real time or not . . . [n]o novelty is seen in charting data real time” (id.).                                       
                         The examiner’s conclusory statements and irrelevant arguments are insufficient                                         
                to discharge the Office’s initial burden of establishing a prima facie case of anticipation.                                    
                Accordingly, we reverse the rejection of claims 15, 17-28, 36-39 and 41-44 under 35                                             
                U.S.C. § 102(b) as anticipated by Akong.                                                                                        
                Obviousness                                                                                                                     
                         The claims stand rejected as follows: claims 15, 18-23, 27, 28, 32-38, 41 and 42                                       
                as unpatentable over Bjornson and Chow; claims 24-26, 43 and 44 as unpatentable                                                 
                over Bjornson, Chow and Ellis, and claims 17 and 39 as unpatentable over Bjornson,                                              
                Chow and Tillotson.  The salient limitations of claims 15, 17-28, 36-39 and 41-44 are                                           
                discussed above.  Claims 32-35, directed to a method for scheduling and performing a                                            
                plurality of fluorescence assays using a plurality of plates each including a plurality of                                      
                wells, require                                                                                                                  
                         storing data representing at least first and second tracks and at least one                                            
                         critical point at which the first and second tracks are tied together in time,                                         



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