Ex Parte FATTOM et al - Page 10



                   Appeal No.  2002-1545                                                             Page 10                      
                   Application No.  08/949,757                                                                                    

                          components in the same molar ratio, from a Streptococcal                                                
                          bacterium and therefore anticipates the now claimed invention.                                          
                   Examiner’s Answer, page 8.                                                                                     
                          Appellants acknowledge that Enterococcus was formerly known as                                          
                   Streptococcus, but that only Streptococcus having the group D antigen, i.e.,                                   
                   Streptococcus D, were placed in the Enterococcus genus.  Appellants cite Ruoff                                 
                   and Deibel to support their contention that Enterococcus differ significantly from                             
                   the other groups of Streptococcus.  See Revised Brief on Appeal, pages 12-13.                                  
                   According to Appellants, “[t]he antigens characterized in Wessman are the group                                
                   antigens for P and U streptococci, respectively, while the presently claimed                                   
                   antigen is characteristic of a subgroup of clinical isolates of one species of                                 
                   Enterococcus, E. faecalis.”  Id. at 14 (emphasis in original).                                                 
                          The examiner acknowledges that Streptococcus and Enterococcus                                           
                   significantly differ, but contends that they are similar is sharing cross-reactive                             
                   antigenic determinants.  See Examiner’ Answer, page 24.  The examiner asserts                                  
                   that “[a]ny antigen that contains these sugars in the claimed amounts would read                               
                   on the claimed antigen.  The presence of cross reactive carbohydrate epitopes,                                 
                   despitegenetic divergence between genera, defined shared carbohydrate                                          
                   antigens between different genera of bacteris.”  Id. at 25.  The examiner also                                 
                   asserts that “[n]o side by side comparison has been provided.  No evidence has                                 
                   been made of record to show that the antigen of the prior art does not induce                                  









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