Ex Parte ROTH et al - Page 4


                 Appeal No.  2003-1167                                                          Page 4                  
                 Application No.  09/195,340                                                                            
                                                                                                                       
                 opinion that the examiner failed to demonstrate that Hubbell discloses each and                        
                 every limitation of the claimed invention.                                                             
                        Accordingly, we reverse the rejection of claims 6, 14, 18, 19 and 24 under                      
                 35 U.S.C. § 102(e) as being anticipated by Hubbell.                                                    
                 THE REJECTION UNDER 35 U.S.C. § 103:                                                                   
                        As discussed above, the examiner recognizes (Answer, page 6) that                               
                 Hubbell does not teach vascularization, or the active agents of the claimed                            
                 invention.  Accordingly, Hubbell alone is not sufficient to establish a prima facie                    
                 case of obviousness.  However, the examiner asserts (id.), “[o]ne skilled in the                       
                 art would be motivated further to include [the] instant active agent since the                         
                 references of Sierra, Hunziker and Marx teach the deliver[y] of these agents at                        
                 the site based on the same principle, that is ‘polymerization at the site’….”                          
                        With emphasis on Hunziker, the examiner asserts (Answer, page 7),                               
                        Hunziker clearly states that the growth factor, Fibroblast growth                               
                        factor is involved in the growth of vascular endothelial cells.                                 
                        Applicant’s [sic] arguments that Hunziker is not directed to                                    
                        vascularization are not found to be persuasive since Hunziker                                   
                        teaches the application of the composition after surgery and                                    
                        naturally the tissue healing involves vascularizaiton.                                          
                 However, Hunziker is directed to repairing defects in cartilage, and appellants                        
                 point out (Brief, page 11) that “cartilage is avascular ([Hunziker], column 1, lines                   
                 37-38).”  Therefore, appellants’ argue (id.), “Hunziker clearly fails to disclose a                    
                 treatment which promotes vascularization or revascularization.”  Appellants find                       
                 the same flaw in the examiner’s reliance on Sierra and Marx, which according to                        
                 appellants “are directed to repairing avascular cartilage.”  Brief, page 12.                           







Page:  Previous  1  2  3  4  5  6  7  Next 

Last modified: November 3, 2007