Ex Parte LI et al - Page 7




                Appeal No. 2004-0275                                                                           
                Application No. 09/09/318,186                                                                  
                presentation of evidence that is pertinent.  In re Dillon, 919 F.2d 688, 692-93, 16            
                USPQ2d 1897, 1901 (Fed. Cir. 1990) (en banc),  cert. denied,  500 U.S. 904                     
                (1991).                                                                                        
                      Appellants argue that the instant claims are not obvious under 35 U.S.C.                 
                §103 in view of the cited references.  Brief, page 12.   Appellants argue that, “one           
                of ordinary skill in the art would not look to bits and pieces of the secondary                
                references in that manner suggested if the references are considered as a                      
                whole.”  Brief, page 6.  Appellants point out that Welch does not describe                     
                synthesizing chiral selectors on a polymeric synthesis resin, Liu does not                     
                describe synthesizing chiral selectors on a resin, and Weingarten fails to disclose            
                forming a parallel library. Brief, pages 5-9.                                                  
                      These attempts to rebut the examiner's prima facie case of obviousness                   
                are unpersuasive.  Obviousness can be established by combining or modifying                    
                the teachings of the prior art to produce the claimed invention where there is                 
                some teaching, suggestion, or motivation to do so found either in the references               
                themselves or in the knowledge generally available to one of ordinary skill in the             
                art.   In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988),  In              
                re Jones, 958 F.2d 347, 350, 21 USPQ2d 1941, 1943 (Fed. Cir. 1992).                            
                      We agree with the examiner that the prior art references provide the                     
                necessary reason, suggestion or motivation to make the claimed invention and                   
                we are not persuaded by appellants’ arguments to the contrary.  Appellants                     

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