Ex Parte VERHEUL-KOOT et al - Page 4



              Appeal No. 2004-0339                                                                Page 4                
              Application No. 09/462,678                                                                                
              (id., page 6) and “it would have been obvious  . . . to add [the] flavonoids of Vester [to]               
              the nutritional composition of [Henningfield], with an expectation to provide a strong                    
              antioxidant activity in plasma and also provide protection to the other antioxidant of                    
              [Henningfield,] i.e., vitamin E from being oxidized” (id., page 4).                                       
                     Appellants argue that Henningfield “does not even mention the oxidative stability                  
              of vitamin E” (Brief, page 5), and, in any case, “the technical fields of [Henningfield] and              
              Vester are distinct and unrelated” (id.), as one “relates to a nutritional product for trauma             
              and surgery patients” while the other “describes a nutritional supplement specifically                    
              designed for improving cardiovascular health” (id.).  Appellants’ points are well taken.                  
                     We see nothing in Henningfield that suggests a recognition that oxidation of                       
              vitamin E might interfere with the efficacy of the nutritional product.  Moreover, while                  
              Henningfield’s and Vester’s compositions are both nutritional in the sense that they are                  
              ingested and metabolized, one is designed to serve as a food substitute, while the other                  
              is merely a food supplement.  In our view, the examiner has unduly focused on the very                    
              limited common ground between Henningfield and Vester (i.e., both describe                                
              compositions containing vitamin E), while completely ignoring their substantial                           
              differences, and we agree with appellants that “one of ordinary skill in the art would lack               
              the motivation to combine [their] teachings (id., pages 4-5).                                             
                     As set forth in In re Kotzab, 217 F.3d 1365, 1369-70, 55 USPQ2d 1313, 1316                         
              (Fed. Cir. 2000) (citations omitted):                                                                     
                     A critical step in analyzing the patentability of claims pursuant to section                       
                     103(a) is casting the mind back to the time of invention, to consider the                          
                     thinking of one of ordinary skill in the art, guided only by the prior art                         
                     references and the then-accepted wisdom in the field. [ ] Close adherence                          
                     to this methodology is especially important in cases where the very ease                           
                     with which the invention can be understood may prompt one “to fall victim                          




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