Ex Parte Douin et al - Page 12


              Appeal No. 2004-0378                                                                                            
              Application No. 09/765,675                                                                                      

                      It may be true that Ziegler would not have motivated those skilled in the art to                        
              add Quatrisoft to Restle’s composition for the same reason that Appellants add                                  
              Quatrisoft LM-200 to their composition, but the prior art need not suggest combining                            
              elements for the same reason Appellants combined them in order to support a prima                               
              facie case under § 103.  See In re Dillon, 919 F.2d 688, 692-93, 16 USPQ2d 1897,                                
              1901 (Fed. Cir. 1990).                                                                                          
                      Appellants also seem to argue that the claimed composition has been shown to                            
              be unexpectedly superior to prior art products.  This argument is not well-developed in                         
              the Appeal Brief, but Appellants do allude to their                                                             
                      demonstrat[ion] that the thickening, the transparency, and the stability of a                           
                      nanoemulsion comprising at least [one] cationic polymer comprising at                                   
                      least one hydrophobic block and at least one hydrophilic block (Quatrisoft                              
                      LM 200), at least one oil, and at least one amphiphilic lipid is greater than                           
                      that of a nanoemulsion in which the at least [one] cationic polymer                                     
                      comprising at least one hydrophobic block and at least one hydrophilic                                  
                      block is replaced with the same amount of Carbopol Ultrez, a crosslinked                                
                      acrylic acid homopolymer.                                                                               
              Appeal Brief, page 5.  The specification states that “[t]he inventors have discovered,                          
              unexpectedly, that oil-in-water nanoemulsions . . . can be thickened with at least one                          
              cationic polymer, for example, at least one cationic polymer chosen from water-soluble                          
              and water-dispersible cationic polymers comprising at least one hydrophobic block and                           
              at least one hydrophilic block.”  Pages 3-4.                                                                    
                      To the extent that Appellants intend to rely on the specification’s working                             
              example as evidence of unexpected results, however, we find the evidence to be                                  
              inadequate to overcome the prima facie case.  It is true that “the PTO must consider                            
              comparative data in the specification in determining whether the claimed invention                              






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