Ex Parte DENEFLE et al - Page 2




              Appeal No. 2004-0456                                                                                     
              Application No. 08/913,699                                                                               

                     The prior art references relied upon by the examiner are:                                         
              Benoit et al. (Benoit)            WO 94/25073                 Nov. 10, 1994                              
              Baer et al. (Baer)                EP 0222591                  May 20, 1987                               
              Perricaudet et al. (Perricaudet)  WO 95/02697                 Jan. 1995                                  
              McLean, et al. (McLean), “Human lecithin-cholesterol acetyltransferase gene: complete                    
              gene sequence and sites of expression,” Nucleic Acids. Research, Vol. 14, No. 23,                        
              pp. 9397-9406 (1986)                                                                                     
              Jolly, D., “Viral Vector Systems for Gene Therapy,” Cancer Gene Therapy, Vol. 1, No.                     
              1, pp. 51-64 (1991)                                                                                      

              Grounds of Rejection                                                                                     
                     Claims 38, 43-45, 48-50, 55 and 56 stand rejected under 35 U.S.C. 103(a), as                      
              obvious over Benoit in view of Baer and McLean.                                                          
                     Claims 38, 43, 45, 46 and 51 stand rejected under 35 U.S.C. 103(a), as obvious                    
              over Benoit in view of Baer and McLean in further view of Perricaudet.                                   
                     Claims 38 and 52-54 stand rejected under 35 U.S.C. 103(a), as obvious over                        
              Benoit in view of Baer and McLean in further view of Jolly.                                              
                     We reverse these rejections.                                                                      


                                                    DISCUSSION                                                         


              35 U.S.C. § 103(a)                                                                                       
                     Claims 38, 43-45, 48-50, 55 and 56 stand rejected under 35 U.S.C. 103(a), as                      
              obvious over Benoit in view of Baer and McLean.                                                          


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