Ex Parte Gormley et al - Page 4



              Appeal No. 2004-0543                                                                  Page 4                
              Application No. 10/010,678                                                                                  
                     Claims 28, 29 and 31-34 specifically require transdermal administration of the                       
              inhibitor.  We agree with the examiner that Atransdermal administration is broader than                     
              skin-patch administration@ (Answer, page 8), but disagree with the examiner=s assertion                     
              that Aappellants prefer the claim language to be understood as >use of [a] transdermal                      
              skin patch=@ (id.).2  Rather, appellants= position is essentially that Atransdermal (>through-              
              the-skin=) administration constitutes a separate and distinct claim limitation from [ ]                     
              topical (>cutaneous=) administration of 5alpha-reductase 2 inhibitors@ (Brief, page 6), and                 
              Athe two routes of administration are in fact not interchangeable@ (id., page 7), because                   
              transdermal administration is systemic and continuous, while topical administration is                      
              local and intermittent (id., pages 7 and 8).                                                                








                                                                                                                         
                     2 The examiner=s interpretation of appellants= argument appears to stem from appellants=             
              statement on page 7 of the Brief that their Aoriginal patent disclosure [(at page 6, lines 22-24 and 32-34)]
              associates topical administration with >solution[s], cream[s], ointment[s], gel[s], lotion[s], shampoo[s] or
              aerosol formulation[s]= . . . [while] transdermal administration is linked to the use of transdermal skin   
              patches only.@                                                                                              














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