Ex Parte Esser et al - Page 8




                     Appeal No. 2005-0393                                                                                                                                              
                     Application 09/536,728                                                                                                                                            
                     based on structural homology and the expectation that they will have similar properties                                                                           
                     with the compounds taught by Olson.                                                                                                                               
                                           Accordingly, Rejection I is reversed.                                                                                                       
                                                                                         II.                                                                                           
                                The examiner argues that York discloses 2-(substituted phenylimino)                                                                                    
                     imidazolidines which are structurally similar to the claimed compounds wherein R1 is                                                                              
                     ethyl, R2 is NR6R7, R6 is methyl, n-propyl, isopropyl, n-butyl, isobutyl, a-butyl, or t-butyl,                                                                    
                     R7 is hydrogen, methyl, ethyl, n-propyl, –butyl, isobutyl, s-butyl or t-butyl, R3 is                                                                              
                     hydrogen, R4 is hydrogen and R5 is ethyl.  Answer, p. 5.  According to the examiner, the                                                                          
                     only difference between the prior art compounds and the compounds described in                                                                                    
                     representative claims 21 and 39 is that R6 is hydrogen atom rather than methyl, ethyl, n-                                                                         
                     propyl, n-butyl, isobutyl, s-butyl, or t-butyl group.  Id.  The examiner points to Example V                                                                      
                     and argues that it would have been obvious to one of ordinary skill in the art  to replace                                                                        
                     the hydrogen atom with a lower alkyl group on the nitrogen atom.  Id., p. 6.                                                                                      
                                In response, the appellants argue that Example V is not within the scope of the                                                                        
                     claims.  Brief, p. 8.  The appellants further argue that in said example, R3 is an -NH2                                                                           
                     group; whereas, in the claimed compound, R2 (the position corresponding to R3 in York),                                                                           
                     is a substituted amino group or a heterocycle.  Id., sentence bridging pp. 8-9.  The                                                                              
                     appellants contend that the examiner has not adequately explained why one skilled in                                                                              
                     the art would have been motivated to modify the prior art compound to arrive at the                                                                               
                     claimed invention.  Id., p. 9.                                                                                                                                    

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