LEE et al. V. DRYJA et al. - Page 2




              Interference No. 105,182                                                     Paper 77                     
              Lee v. Dryja                                                                 Page 2                       
              I.     Introduction                                                                                       
                     Interference 105,182 was declared on 22 September 2004 between junior party                        
              WEN-HWA LEE and EVA Y-H.P. LEE (“Lee”) and senior party THADDEUS P. DRYJA,                                
              STEPHEN FRIEND and DAVID W. YANDELL (“Dryja”).  Lee is involved in the                                    
              interference on the basis of U.S. Patent 5,998,134 (“the ‘134 patent”), issued 7                          
              December 1999, based on U.S. application 08/482,627 (“the ‘627 application”).  Dryja is                   
              involved in the interference on the basis of U.S. application 09/387,158 (“the ‘158                       
              application”) filed 31 August 1999.  The subject matter of the interference is defined by                 
              one count, i.e., Lee ‘134 patent claim 1 or Dryja ‘627 application claim 22, and is                       
              directed to a method of detecting a mutated retinoblastoma (“RB”) nucleic acid in a                       
              sample by using an isolated cDNA which encodes a full length, wild-type RB protein as                     
              a hybridization probe. Lee ‘134 patent claims 1-4 and Dryja ‘158 application claims 22,                   
              23 and 49 were designated as corresponding to the count.  [Paper 1.]                                      
                     Among the motions filed during the motion phase of the interference was Dryja                      
              revised motion 2.  Dryja revised motion 2 sought judgment that Lee ‘134 patent claims                     
              1-4 are barred on the basis of interference estoppel or res judicata because Lee                          
              received an adverse decision in prior interferences 103,426 (“the ‘426 interference”)                     
              and 104,259 (“the ‘259 interference”) (Paper 33).  Dryja revised motion 2 was granted                     
              for reasons set forth in the “DECISION - PRELIMINARY MOTIONS - Bd.R. 125(a)”                              
              (Paper 76) issued concurrently with this judgment and is a dispositive motion.  As a                      
              result of granting Dryja revised motion 2, Lee no longer has any patentable claims                        
              corresponding to the sole count in the interference.  Since Lee no longer has any                         






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