Ex Parte 5855920 et al - Page 15




               Appeal No. 2005-2593                                                                               15                 
               Application No. 90/005,867                                                                                            

               possible adverse side effects associated with estrogen administration.9                                               
                       Second, in his Declaration, George M. Fahy states (Declaration of George M.                                   
               Fahy dated March 19, 2002, at 3):                                                                                     

                               10. The ‘991 Application [Fahy] does not give any indication of                                       
                       the possible effect of administering HGH plus two “unrelated” hormones,                                       
                       though                                                                                                        
                       it points out, in the “Background of the Invention” section, interest in                                      
                       multiple hormones among proponents of anti-aging medicine.                                                    
                               11. To my knowledge, there can be side effects or health risks                                        
                       associated with hormone supplementation such as increased serum levels                                        
                       of insulin with HGH supplementation that increases the risk of heart                                          
                       disease, and possibly an increased risk of prostate cancer in men with                                        
                       testosterone supplementation[.]                                                                               
               Significantly, Dr. Fahy does not discuss any significant health risks or possible adverse                             
               side effects associated with administering estrogen in combination with human growth                                  
               hormone and DHEA.                                                                                                     
                       For the reasons set forth above, the rejection of claim 25 under 35 U.S.C. § 103                              
               is affirmed.                                                                                                          
                       F.      Rejection of claims 26 and 27 under 35 U.S.C. § 103                                                   
                       Claims 26 and 27 are rejected under 35 U.S.C. § 103 as being unpatentable over                                
                                                                                                                                    
                       9  Fahy does not identify the male contraceptive referred to in the disclosure.  Nevertheless, the appellant  
               has failed to establish that estrogen is used as a male contraceptive.                                                








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