Ex Parte Andela et al - Page 2


              Appeal No. 2006-0201                                                                  Page 2                 
              Application No. 10/125,272                                                                                   

              pelleting.  Preferred manufacturing protocols in the feed industry involve steam pelleting                   
              where the feed is subjected to steam injection(s) prior to pelleting, a process called                       
              conditioning. . . . During this conditioning process temperatures may rise to 60-95°C.                       
              The combined effect of high moisture content and high temperature is detrimental to                          
              most enzymes.”  Pages 1-2.                                                                                   
                     The specification discloses “a process for the preparation of an enzyme-                              
              containing granulate suitable for use in an animal feed, the process comprising                              
              processing an enzyme, a solid carrier, optionally additives and water . . . to obtain                        
              enzyme-containing granules, drying the granules, and coating the dried granules with                         
              polyethylene glycol.”  Page 3.                                                                               
                     The specification reports that coating the granules with polyethylene glycol (PEG)                    
              “protect[s] against the formation of dust” and “provide[s] a good pelleting stability of the                 
              granule”; i.e., results in less loss of enzyme activity during pelleting.  Page 4, lines 1-2                 
              and 7-8.  Moreover, granules coated with PEG dissolve twenty times faster than                               
              granules with a fat-type coating, and “[a] short dissolution time significantly improves the                 
              bioavailability of the enzyme to the animal.”  Page 4, lines 3-7.                                            
                                                       Discussion                                                          
              1.  Claim construction                                                                                       
                     Claims 1 and 3-36 are on appeal.  Claim 1 is the only independent claim and                           
              reads as follows:                                                                                            
                     1. A process for the preparation of an enzyme-containing granulate suitable                           
                            for use in animal feed, the process comprising:                                                
                            (a) mixing a feed enzyme, a solid carrier, water, and at least one                             
                                    additive in an effective amount;                                                       





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