Ex Parte Herron et al - Page 9




               Appeal No. 2006-1563                                                                                               
               Application No. 09/839,778                                                                                         
               respect to Claim 8.                                                                                                
                      We find the examiner has presented evidence to support a prima                                              
               facie case of anticipation which has not been convincingly rebutted by appellants.  The                            
               rejection of the claims for anticipation is affirmed.                                                              

               Obviousness                                                                                                        
                      Claims 7 and 10-12 stand rejected under 35 U.S.C. § 103(a) over Jackowski in                                
               view of Sawai.   We select claim 10 as a representative claim for purposes of this                                 
               rejection.                                                                                                         
                      In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden                            
               of presenting a prima facie case of obviousness.  See In re Rijckaert, 9 F.3d 1531,                                
               1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993).   A prima facie case of obviousness is                                
               established when the teachings from the prior art itself would appear to have suggested                            
               the claimed subject matter to a person of ordinary skill in the art.  In re Bell, 991 F.2d                         
               781, 783, 26 USPQ2d 1529, 1531 (Fed. Cir. 1993).  An obviousness analysis requires                                 
               that the prior art both suggest the claimed subject matter and reveal a reasonable                                 
               expectation of success to one reasonably skilled in the art.  In re Vaeck, 947 F.2d 488,                           
               493, 20 USPQ2d 1438, 1442  (Fed. Cir. 1991).  With this as background, we analyze                                  
               the prior art applied by the examiner in the rejection of the claims on appeal.                                    
                      According to the examiner (Answer, page 5)                                                                  
                              Jackowski provides several examples of methods to determine the                                     
                      extent or amount of binding between the antibodies and markers (see for                                     
                      example, col. 28, lines 8-38.)  Jackowski teaches that other methods for                                    
                      determining the presence and amount of a marker or analyte may be used                                      
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