Ex Parte Granger et al - Page 5


             Appeal No. 2006-1801                                                             Page 5               
             Application No. 10/007,869                                                                            

             2.  Rejection under 35 U.S.C. § 103                                                                   
                    Claims 1, 2, 4-7, 9-12, and 14-18 stands rejected under 35 U.S.C. § 103(a), as                 
             unpatentable over Burger2 and Granger3 in view of Liu4 and Suares5 and Remington6.                    
                    Each of Burger and Granger describes compositions for application to the skin                  
             which contain retinoids in combination with other components that enhance retinoid                    
             activity.  See, Examiner’s Answer, pages 4-5.  Retinoid and booster concentrations are                
             disclosed in Burger (e.g., column 2, lines 61-65, and column 2, lines 3-7, respectively).             
             Several of the boosters recited in instant claim 1 are disclosed, e.g., damascone                     
             (Burger, column 3, line 45), alpha ionone (Burger, column 3, lines 46), and climbazole                
             (Granger, column 4, lines 19), but as residing in the same composition as the retinoid.               
                    The problem of retinoid stability in preparing skin cosmetics is described in Liu.             
             Several approaches to resolving it are disclosed, including supplying components in                   
             separate containers which are combined just prior to use (Liu, column 2, lines 60-61)                 
             and formulating retinoid in an oil-in-water emulsion (Liu, column 3, lines 15-20).                    
             Appellant admitted these to be prior art in their own application.  See, e.g.,                        
             Specification, page 1, line 27-page 3, line 15.  Aluminum packaging is mentioned by Liu               
             as a way to protect retinoids from degradation.  Liu, column 12, lines 50-55.  (Compare               
             claim 1: “first compartment for storing [retinoid] is made out of aluminum.”)  The                    
             examiner relied upon Remington for this teaching, but this was unnecessary since it                   
             was redundant to Liu’s disclosure.                                                                    

                                                                                                                   
             2 Burger et al. (Burger) U.S. Patent No. 5,759,556 issued Jun. 2, 1998                                
             3 Granger et al. (Granger) U.S. Patent No. 5,716,627 issued Feb. 10, 1998                             
             4 Liu et al. (Liu) U.S. Patent No. 5,976,555 issued Nov. 2, 1999                                      
             5 Suares et al. (Suares) U.S. Patent No. 5,914,116 issued Jun. 22, 1999                               
             6 Remington’s Pharmaceutical Sciences (1990) p. 1511-1512                                             





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