Ex Parte Krieger et al - Page 1




                         The opinion in support of the decision being entered today was not written         
                               for publication and is not binding precedent of the Board.                   


                      UNITED STATES PATENT AND TRADEMARK OFFICE                                             
                                                __________                                                  
                           BEFORE THE BOARD OF PATENT APPEALS                                               
                                        AND INTERFERENCES                                                   
                                                __________                                                  
                                        Ex parte MONTY KRIEGER,                                             
                                 ANNE BRAUN and HELENA E. MIETTINEN                                         
                                                __________                                                  
                                           Appeal No. 2006-1993                                             
                                         Application No. 10/147,651                                         
                                                __________                                                  
                                          HEARD: August 8, 2006                                             
                                                __________                                                  
               Before ADAMS, MILLS, and GREEN, Administrative Patent Judges.                                
               GREEN, Administrative Patent Judge.                                                          

                                          DECISION ON APPEAL                                                
                      This is a decision on appeal under 35 U.S.C. § 134 from the examiner’s                
               final rejection of claims 1-8 and 10-16.  Claims 1 and 13 are representative of the          
               claims on appeal, and read as follows:                                                       
                      1. A method for identifying compounds for treating or                                 
                      preventing atherosclerosis or cardiovascular disease comprising                       
                            administering compounds that may have an effect on                              
                      disorders selected from the group consisting of cardiac fibrosis,                     
                      myocardial infarction, defects in electrical conductance,                             
                      atherosclerosis, unstable plaque, and stroke to a mouse having                        
                      decreased expression of active SR-BI and Apo-E wherein the                            
                      mouse develops atherosclerotic plaque in the aortic sinuses and                       
                      progressive heart block and                                                           






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