Ex Parte BEHR et al - Page 1


                         The opinion in support of the decision being entered today was not written          
                                for publication and is not binding precedent of the Board.                   

                       UNITED STATES PATENT AND TRADEMARK OFFICE                                             
                                                __________                                                   
                           BEFORE THE BOARD OF PATENT APPEALS                                                
                                         AND INTERFERENCES                                                   
                                                __________                                                   
                                      Ex parte THOMAS M. BEHR and                                            
                                         DAVID M. GOLDENBERG                                                 
                                                __________                                                   
                                           Appeal No.  2006-2417                                             
                                         Application No.  09/200,791                                         
                                                __________                                                   
                                                 ON BRIEF                                                    
                                                __________                                                   
                Before SCHEINER, ADAMS, and GREEN, Administrative Patent Judges.                             
                ADAMS, Administrative Patent Judge.                                                          

                                          DECISION ON APPEAL                                                 
                      This is a decision on the appeal under 35 U.S.C. § 134 from the                        
                examiner’s final rejection of claims 1-9, 11-21, 23-29, and 31-41, which are all             
                the claims pending in the application.                                                       
                      Claim 1 is illustrative of the subject matter on appeal and is reproduced              
                below:                                                                                       
                   1. A method of reducing kidney retention of a protein conjugate in a patient,             
                      comprising administering to said patient one or more compounds selected                
                      from the group consisting of D-lysine, poly-lysine having a molecular                  
                      weight in the range 1-60 kD, pharmaceutically acceptable salts thereof                 
                      and carboxyl derivatives thereof, wherein said protein conjugate has a                 
                      molecular weight that is not greater than about 60 kD                                  
                      wherein the pharmaceutically acceptable salt and carboxyl derivative of                
                      polylysine has a molecular weight in the range 1-60 kD,                                
                      whereby said compound or compounds reduce kidney retention of said                     
                      conjugates.                                                                            





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