Ex Parte Desponds et al - Page 12


              Appeal No. 2006-2428                                                                    Page 12                  
              Application No. 10/362,500                                                                                       

              212, 214, 40 USPQ 665, 667 (CCPA 1939) (emphasis and bracketed material in                                       
              original)).  Moreover, anticipation is not established by selecting isolated elements from                       
              unrelated portions of a reference and combining them to arrive at the claimed invention.                         
              See In re Arkley, 455 F.2d 586, 587-588, 172 USPQ 524, 526 (CCPA 1972).                                          
                      In our view, Uneme does not explicitly or inherently disclose performing the                             
              chlorination step in the presence of acetonitrile, as recited in claim 2.  Rather, by                            
              attempting to construct a single anticipating embodiment from portions of the reference                          
              which are not necessarily related, the rejection engages in the type of analysis                                 
              prohibited by Arkley.                                                                                            
                      As urged by Appellants (Appeal Brief, page 5), Uneme discloses that the                                  
              chlorinating step may be performed without a solvent, or in “a solvent that is inert under                       
              reaction conditions,” preferably “halogenated hydrocarbons such as dichloromethane,                              
              chloroform, carbon tetrachloride, 1,2-dichloroethane, 1,1,1-trichloroethane and 1,1,2,2-                         
              tetrachloroethane.”  Column 3, lines 55-60.  As urged by the examiner (Answer, page 3),                          
              Uneme discloses that, after the chlorinating step, the aminating step may be performed                           
              without isolation of the intermediate compound, using acetonitrile as the solvent.  Column                       
              6, lines 19-34.                                                                                                  
                      However, we see nothing in the reference that necessarily, or inherently,                                
              discloses the use of acetonitrile as the solvent in the initial chlorinating step, as required                   
              by claim 2.  Uneme states that the intermediate compound resulting from the chlorinating                         
              step “may be isolated and purified, or in some cases, it can be reacted with an aminating                        
              agent without isolation and purification.”  Column 6, lines 19-21 (emphases added).                              
              Acetonitrile is one of many suitable solvents for the aminating step.  Id. at lines 27-47.                       





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