Ex Parte HOPKINS - Page 5


                 Appeal No. 2006-2569                                                       Page 5                   
                 Application No. 09/485,245                                                                          

                 8 mer range, and that such primers would be desirable in a dried system.  See id.                   
                 at 6-7.  Shen, according to appellant, teaches dried 22-mer and 48-mer primers,                     
                 “but fails to suggest that such dried primers should be shortened, or, alteratively                 
                 any reason why the short primers of Godiska should be dried.”  Id. at 7.                            
                        Appellant’s arguments are not found to be convincing.  With respect to                       
                 appellant’s argument that Godiska and Shen fail to teach the desirability of short                  
                 primers (6-8 mers) in a dried primer system or that 6-8 mers would behave                           
                 differently with respect to self-priming activity and labeling intensity than do 9-                 
                 mers, the motivation to combine references does not have to be identical to that                    
                 of appellant to establish obviousness.  See In re Kemps, 97 F.3d 1427, 1430, 40                     
                 USPQ2d 1309, 1311 (Fed. Cir. 1996).  In the rejection before us, Godiska is cited                   
                 for teaching a priming reaction using random 6-mer (hexamer) primers.  See                          
                 Godiska, col. 8, lines 29-30.  Shen, although not teaching 6-mer to 8-mer random                    
                 primers, as noted by the rejection, teaches the desirability of providing dried                     
                 reagents.  Thus, it would have been obvious to dry the reagents of Godiska as                       
                 taught by Shen to achieve the advantages of Shen of being useful in shipping                        
                 and storage of commercial preparations due to increased stability, even when                        
                 stored for prolonged periods or when stored at high temperatures.                                   














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