Ex Parte Petersen et al - Page 22


             Appeal No. 2006-2627                                                            Page 22                
             Application No. 09/947,833                                                                             

             The common ground:                                                                                     
                    Both O’Leary and Yim teach a composition for use in bone repair that comprises                  
             a common core of ingredients which comprise:                                                           
                    (1) hydroxypropyl methylcellulose (a cellulose derivative); and                                 
                    (2) a mixing solution.                                                                          
             As discussed above, this is undisputed by the majority.                                                


             The differences:                                                                                       
                    The prior art of record does not teach a composition that combines both calcium                 
             sulfate, demineralized bone and cancellous bone together with a common core of                         
             ingredients that comprises hydroxypropyl methylcellulose and a mixing solution.                        
             Instead, O’Leary takes this common core of ingredients and adds demineralized bone;                    
             and Yim takes this common core of ingredients and adds calcium sulfate.  For his part                  
             Wironen teaches a bone repair composition comprising a gelatin (which may be                           
             “thermally cross-linkable”) demineralized bone, cancellous bone, BMP, and a reagent                    
             that “enhances the range of manipulable characteristics of strength and osteoinduction                 
             exhibited by the composition.”  Wironen, page 5, line 21 to page 6, line 9.                            


             The level of skill in the art:                                                                         
                    In the background section of their specification (pages 1-2) appellants discuss a               
             number of prior art references that establish the state of this art, and level of skill in this        









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