Ex Parte Selzer - Page 2

                 Appeal No. 2006-0760                                                                                  
                 Application No. 10/312,417                                                                            

                 claim 13 as representative of the first grouping.  For the second grouping,                           
                 the claims stand or fall together because Appellant has not provided separate                         
                 arguments for patentability of any of the claims.  We select claim 20 as                              
                 representative claim of the second grouping.  37 C.F.R. § 41.37(c)(1)(vii).                           

                        13. A dermal therapeutic system comprising as an active                                        
                        pharmaceutical ingredient for the treatment of symptoms associated                             
                        with irritation from degenerative joint disorders and for the treatment                        
                        of postoperative and menstrual pain at least one COX-2 inhibitor,                              
                        characterized in that the COX-2 inhibitor is a 3-aryl-4-(4-                                    
                        methylsulfonylphenyl)-2(H5) furanone or a 4-[5-aryl-3-                                         
                        (trifluoromethylpyrazol- 1-yl]benzenesulfonamide.                                              
                        20. A dermal therapeutic system for the delivery of a medical                                  
                        substance to the skin, which consists of:                                                      
                        a) a support layer, which is impermeable to the medical substance;                             
                        b) a reservoir or matrix layer that contains the medical substance                             
                        wherein said medical substances consists of:                                                   
                               1. at least one COX-2 inhibitor wherein said COX-2 inhibitor is                         
                               selected from the group consisting of 3-aryl-4-(4-                                      
                               methylsulfonylphenyl)-2(H5) furanones and 4-[5-aryl-3-                                  
                               (trifluoromethylpyrazol-1-yl]benzenesulfonamides; and                                   
                               2.  optionally, at least one compounds selected from the group                          
                               consisting of a plasticizers, tackifiers, stabilizers, fillers, carrier                 
                               and permeation enhancer(s);                                                             
                        wherein, said permeation enhancer(s), when present, is (are) a                                 
                        compound selected from the group consisting of fatty alcohols, fatty                           
                        acids, polyoxyethylene fatty alcohols ethers, sorbitan monolaurate,                            
                        long-chain fatty acids with methyl, ethyl or isopropyl alcohols, esters                        
                        of fatty alcohols with acetic or lactic acid, and oleic acid                                   
                        diethanolamine, and                                                                            
                        wherein, when a reservoir layer is present, said reservoir layer                               
                        optionally contains a high viscosity liquid, a semisolid matrix, a                             
                        thixotropic matrix, and/or a gel former;                                                       
                        c) optionally, a control membrane;                                                             


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