Ex Parte Song et al - Page 8

                Appeal 2006-2175                                                                             
                Application 10/122,855                                                                       
                (explaining that the disclosure of a multitude of effective combinations does                
                not render any particular formulation less obvious).                                         
                      Therefore, it would have been prima facie obvious to use                               
                “‘Rapidase’” as the amylase enzyme in the liquid detergent compositions                      
                exemplified by Severson, Jr. in Example I, particularly compositions D or E.                 
                The resulting compositions (and the process of making them) would satisfy                    
                each limitation of claims 1, 8 and 13.                                                       
                      Appellants’ assertion of unexpected results is unpersuasive for two                    
                reasons.                                                                                     
                      First, the Appellants’ claimed invention is not compared to the closest                
                prior art.  Rather, Appellants’ Table 1 on page 5 of their Specification                     
                compares their preferred, though not claimed, alpha amylase enzyme (i.e.,                    
                “Duramyl”) with a detergent composition having the alpha amylase enzyme                      
                (i.e., “Termamyl”) expressly excluded by the language of the claims.  The                    
                required comparison should have been between a composition using                             
                “‘Rapidase,’” the non-TERMAMYL® alpha amylase enzyme, disclosed by                           
                Severson, Jr., and a TERMAMYL® containing detergent composition.                             
                      Second, the evidence of unexpected results is not commensurate in                      
                scope with the claims such evidence is meant to support.  Appellants’                        
                evidence of unexpected results consists of a comparison of a detergent                       
                composition made using “Termamyl” with a detergent composition made                          
                using “Duramyl.”  However, Appellants’ claims do not require that                            
                “Duramyl” be used as the alpha amylase enzyme.  Moreover, Appellants’                        
                compositions allegedly showing unexpected results include non-enzyme                         
                ingredients (e.g., K2SO4, polyacrylate thickener, Protease (4% active),                      



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