Ex Parte Barrett et al - Page 7

                Appeal 2006-3020                                                                                   
                Application 10/109,374                                                                             
                       Appellants contend:                                                                         
                       Dereu . . . is limited to therapeutic use for treating                                      
                       inflammation [and] has nothing to do with imaging                                           
                       inflammation. . . .  Dereu . . . fails to disclose a chelator or                            
                       metal suitable for imaging.                                                                 
                              The Dereu reference provides no suggestion to modify                                 
                       the reference to add a chelator . . . .                                                     
                              Despite the lack of any teaching or suggestion from                                  
                       the Dereu reference concerning modification to allow                                        
                       imaging, the Dunn reference is supplied to disclose a                                       
                       chelator.  Appellants see no motivation in the references                                   
                       themselves to combine their teachings. . . .                                                
                              . . . .                                                                              
                              Even had the Examiner found a motivation in the                                      
                       references, there is little reason to suspect success.                                      
                (Br. 8-9 (emphasis Appellants’).)                                                                  
                       We frame this third issue:  Would the teachings of Dereu and Dunn                           
                have motivated one of ordinary skill in the art to make the invention of claim                     
                39, with a reasonable expectation of success?                                                      

                                        FINDINGS OF FACT                                                           
                Claim Interpretation                                                                               
                       1.  The compounds of claim 39 require “a Leukotriene B4 (LTB4)                              
                receptor binding moiety comprising an aryl or heteroaryl alkyl ether” and “a                       
                chelator” but otherwise are not limited.                                                           
                       2.  Claim 39 is defined by functional terms, except for the “aryl or                        
                heteroaryl alkyl ether” group.                                                                     
                       3.  The Specification defines “chelator” to mean “the moiety or group                       
                on a reagent that binds to a metal radionuclide through the formation of                           
                chemical bonds with one or more donor atoms.”  (Spec. 17: 0412.)                                   


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