Ex Parte Danielson et al - Page 4

                Appeal 2006-3086                                                                                   
                Application 10/260,882                                                                             
                composition comprising simethicone.  Stevens teaches that simethicone is                           
                one of the active ingredients in the pharmaceutical composition (Stevens,                          
                col. 1, ll. 42-55).  Stevens teaches that fillers and lubricants may also be                       
                added as excipients in the pharmaceutical composition comprising                                   
                simethicone (Stevens, col. 5, ll. 35-64).  The Examiner relies on Wehling                          
                and Crowley for a teaching that it would have been obvious to modify                               
                Stevens’ composition by using magnesium carbonate as the lubricant or                              
                filler (Answer 4).  This is, however, exactly what Stevens expressly states                        
                that one should not do.  Specifically, when formulating an antacid with                            
                simethicone “it is necessary to separate the simethicone from the antacid to                       
                avoid the inactivation of the simethicone” (Stevens, col. 1, ll. 23-27).                           
                       Therefore, the rationale set forth by the Examiner is contrary to the                       
                express teachings in the prior art relied upon and would lead to the                               
                inactivation of one of the active agents in Steven’s composition.  As                              
                Appellants explain,                                                                                
                       if a proposal for modifying the prior art in an effort to attain a                          
                       claimed invention causes the art to become inoperable or                                    
                       destroys its intended function, then the requisite motivation to                            
                       make the modification would not have existed.  See In re                                    
                       Fritch, 972 F.2d 1260, 1265 n. 12, 23 U.S.P.Q.2d 1780, 1783 n.                              
                       12 (Fed. Cir. 1992).                                                                        
                                                                                                                  
                (Reply Br. 5.)  We agree, and the rejection of claims 2-11 and 13-32 under                         
                35 U.S.C. § 103(a) as unpatentable over the combination of Stevens and                             
                either Wehling or Crowley is reversed.                                                             






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