Ex Parte Eastman et al - Page 9

                Appeal 2006-3381                                                                               
                Application 10/162,317                                                                         
                          1. Brackett teaches the slide cassette for a tissue specimen and                     
                             method basically as claimed, with a fluid being applied between                   
                             the flexible film window and cover slip.  Examiner asserts that                   
                             Focht teaches a fluid port in a similar slide unit, but for live                  
                             cells and states “[i]t would have been obvious to the ordinarily                  
                             skilled artisan at the time of the invention to include such                      
                             means in Brackett’s device in order to allow the insertion of                     
                             various types of fluids into the specimen-containing cavity.”                     
                             We concur with regard to claims 25 and 40.                                        
                          2. Appellants argue that “…Brackett does not described [sic] any                     
                             insertable fluid, and Focht fails to mention the index of                         
                             refraction of its fluid.”  We agree that the prior art does not                   
                             sufficiently render Claim 50 obvious, as the index of refraction                  
                             is not taught as being that of the tissue sample, and we reverse                  
                             the rejection of that claim.                                                      
                D. With regard to the rejection of claims 34, 35, 37, 45, 47, 51, 52, 58,                      
                59, and 64 under 35 U.S.C. § 103(a) for being obvious over Brackett in view                    
                of Stein:                                                                                      
                          1. We find that Stein teaches the use of a confocal microscope                       
                             with a rotating holder for microscope slides.  The Examiner                       
                             asserts that it would be obvious to use a confocal microscope as                  
                             disclosed by Stein with the slide-cassette of Brackett, instead of                
                             a conventional microscope disclosed by Brackett, as claimed in                    
                             the noted claims.  Appellants repeat the arguments above for                      
                             claims 23, 33 and 58.  We find the substitution of microscopes                    

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