Ex Parte Baker et al - Page 8

                 Appeal No. 2007-0083                                                                                 
                 Application No. 10/174,574                                                                           

                 the earlier-filed applications provides a disclosure sufficient to satisfy the                       
                 first paragraph of § 112, and none can be relied on for priority under § 120.                        
                        The effective filing date of the present application is its actual filing                     
                 date:  June 18, 2002.  Tang qualifies as prior art and Appellants do not                             
                 dispute that it discloses an antibody that binds to the polypeptide of SEQ ID                        
                 NO:32.  Tang therefore anticipate claim 25.  Claims 26-29 fall with claim 25.                        
                 4.  ANTICIPATION BY RUBEN                                                                            
                        Claims 25-29 stand rejected under 35 U.S.C. § 102(b) as anticipated                           
                 by Ruben.  In the Examiner’s Answer, the Examiner provided the following                             
                 citation for Ruben:  “Ruben et al. WO 98/04825.”  Page 3.  In the Form                               
                 PTO-892 that accompanied the Office action mailed Nov. 18, 2004,                                     
                 however, Ruben is cited as “WO 98/40483.”  In their brief, Appellants direct                         
                 their arguments to the reference cited in the Examiner’s Answer, which does                          
                 not appear to be in the official Image File Wrapper.                                                 
                        Since it is unclear from the record (1) what reference the Examiner                           
                 intends to rely on; and (2) whether Appellants had proper notice of the basis                        
                 of the rejection and an opportunity to respond to it, we will vacate the                             
                 rejection based on Ruben.                                                                            
                                                    SUMMARY                                                           
                        We affirm the rejections for lack of patentable utility because the                           
                 evidence of record does not support Appellants’ position that PRO270                                 
                 would be expected to share the activity of thioredoxin.  We affirm the                               
                 anticipation rejection based on Tang and vacate the rejection based on                               
                 Ruben.                                                                                               



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