Ex Parte Arbiser - Page 4

                 Appeal No. 2007-0091                                                                                 
                 Application No. 09/765,491                                                                           

                 curcuminoid-containing polymer formulation for implantation.  The claim                              
                 again requires administration to an “individual in need of treatment,”                               
                 requiring treatment of an individual suffering from one of the recited                               
                 disorders, and states that “an effective amount . . . to inhibit angiogenesis” is                    
                 administered.                                                                                        
                        Claim 17 is similar to claim 4 but includes a broader list of disorders                       
                 and a narrower list of compounds:  the disorders include all those in claim 4                        
                 along with rosacea and eczema, but the compounds are limited to                                      
                 collagenase-inhibiting tetracyclines and angiogenesis-inhibiting sulfated                            
                 polysaccharides.                                                                                     
                 2.  INDEFINITENESS                                                                                   
                        Claims 4-6 and 17 stand rejected under 35 U.S.C. § 112, second                                
                 paragraph, as indefinite.  The Examiner argues that                                                  
                        [t]he term “amount effective” in claims 4 and 17 is indefinite                                
                        since it is not clear what are the “effective amount[s]” to be                                
                        employed in the active agents (collagenase inhibitors,                                        
                        angiogenic  fumagillin  derivatives, . . .  )  in  order  to  inhibit                         
                        angiogenesis without clear guidelines of effective amounts of                                 
                        the agents being utilized.                                                                    
                 (Answer 5.)                                                                                          
                        Appellant argues that “effective amount” is “a common and generally                           
                 acceptable term for pharmaceutical claims. . . . An effective amount of the                          
                 angiogenesis inhibitor is an amount as required to alleviate the symptoms of                         
                 the particular disorder being treated.”  (Br. 9, citing page 14, lines 28-29 of                      
                 the Specification.)                                                                                  
                        We will reverse this rejection.  “A claim is indefinite if, when read in                      
                 light of the specification, it does not reasonably apprise those skilled in the                      

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