Ex Parte Slavtcheff et al - Page 16

                Appeal 2007-0321                                                                                 
                Application 10/669,547                                                                           

                formulated as a cream containing “about 50% . . . of an emollient” (id. at                       
                col. 5, ll. 46-51).  LaHann discloses that suitable emollients include mineral                   
                oil (id. at col. 3, ll. 40-41).                                                                  
                       Thus, one of ordinary skill in the art would have expected from                           
                LaHann that pre-treating skin with compositions containing significant                           
                amounts of lipophilic materials would not interfere with the action of a                         
                thioglycolate depilatory.  Moreover, it is well settled that “unexpected                         
                results must be established by factual evidence.”  In re Geisler, 116 F.3d                       
                1465, 1470, 43 USPQ2d 1362, 1365 (Fed. Cir. 1997).  Appellants have                              
                provided no evidence that the cited results were unexpected.  “Attorney’s                        
                argument in a brief cannot take the place of evidence.”  In re Pearson, 494                      
                F.2d 1399, 1405, 181 USPQ 641, 646 (CCPA 1974).  Appellants therefore                            
                have not shown that one of ordinary skill would have considered it                               
                unexpected that a thioglycolate depilatory would work when applied to an                         
                area pretreated with lipophilic materials.                                                       
                       Appellants argue that Orlow fails to remedy the deficiencies of                           
                LaHann and Michaels because Orlow fails to disclose using high levels of                         
                lipophilic materials for pre-treating chemically depilated skin, and because                     
                Orlow fails to disclose the instructions required by claim 7 (id.).                              
                       We are not persuaded by this argument.  When a kit claim contains                         
                written instructions that merely recite the way in which the other                               
                components of the kit must be used, “the printed matter is not functionally                      
                related to the substrate, [and] the printed matter will not distinguish the                      
                invention from the prior art in terms of patentability.”  In re Ngai, 367 F.3d                   
                1336, 1339 (Fed. Cir. 2004).  Thus, instructions regarding the way the                           


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