Ex Parte Ames et al - Page 6

                Appeal No. 2007-1138                                                                         
                Application No. 10/304,918                                                                   

                applicant to prove that the subject matter shown to be in the prior art does                 
                not possess the characteristic relied on.”  In re Swinehart, 439 F.2d 210,                   
                212-13, 169 USPQ 226, 229 (CCPA 1971); In re Best, 562 F.2d 1252, 1255,                      
                195 USPQ 430, 433-34 (CCPA 1977).  In view of Perricone’s teaching of                        
                carriers for topical compositions that also appear suitable for oral                         
                administration, we find there is sufficient evidence to reasonably presume                   
                that the suggested topical composition is “orally administrable,” shifting the               
                burden to Appellants to show otherwise.                                                      
                      Appellants argue that the prior art relied upon by the Examiner                        
                teaches topical compositions which would be “incompatible with an orally                     
                administrable form.”  (Br. 3.)  We agree to the extent that when impregnated                 
                in a wound dressing, the composition would hardly be suitable for                            
                administration by mouth.  However, Perricone teaches topical formulations,                   
                e.g., using water, which are in a physical form compatible with oral                         
                administration.  Appellants assert that “the disclosed topical vehicles” in the              
                cited prior are not compatible with oral use, but provide no evidence to                     
                substantiate this position.                                                                  
                      Accordingly, we affirm the rejection.  Because our reasoning differs                   
                from the Examiner’s, we designate this as a new ground of rejection under                    
                37 C.F.R. § 41.50(b) to provide Appellants with the opportunity to respond                   
                to it.                                                                                       
                                             OTHER ISSUES                                                    
                      Should prosecution resume in this application, the Examiner should                     
                consider the relevance of the following prior art:                                           



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