Ex Parte Belanoff - Page 9

                Appeal  2007-1155                                                                                
                Application 10/230,575                                                                           
                in Schatzberg ‘046 overlaps the patient population in Appellant’s claimed                        
                method.                                                                                          
                       There can be no doubt that Schatzberg ‘046’s invention is directed to                     
                a method of inhibiting progression toward dementia by administering a                            
                glucocorticoid receptor antagonist in an amount that is effective to treat                       
                dementia.  However, Schatzberg ‘046 requires that the patient being treated                      
                is determined to have a score of between 21 and 29 on the Folstein Mini                          
                Mental Status Exam.  The Examiner makes no findings on this record to                            
                establish a nexus between the patient treated in Schatzberg ‘046 and the                         
                patient treated in Appellant’s claims.  Instead, the Examiner simply asserts                     
                that the patient population is the same.  In our opinion, the factual evidence                   
                before us is insufficient to sustain the rejection.  Conclusions of obviousness                  
                must be based upon facts, not generality.  In re Warner, 379 F.2d 1011,                          
                1017, 154 USPQ 173, 178 (CCPA 1967); In re Freed, 425 F.2d 785, 787,                             
                165 USPQ 570, 571 (CCPA 1970).                                                                   
                       Accordingly, we reverse the rejection of claims 1-15 under the                            
                judicially created doctrine of obviousness-type double patenting as being                        
                unpatentable over claims 1-20 of Schatzberg ‘046.                                                

                                                CONCLUSION                                                       
                       In summary, we reverse all rejections of record.                                          

                                                 REVERSED                                                        





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