Ex parte ARCHIBALD et al. - Page 6




          Appeal No. 95-3340                                                           
          Application  07/939,172                                                      
          respective to this difference, first is that the claimed compound            
          is a homolog of the proffered compound and second that the                   
          claimed compound is so structurally similar to the proffered                 
          compound that one of ordinary skill in the art would have been               
          motivated to make the claimed compound and to expect it to                   
          possess the same properties as the Rohrback compounds.  The                  
          examiner relies upon the secondary references in combination with            
          Rohrback to provide a method of making the claimed compound.                 





                    As stated by the court in In re Jones, 958 F.2d 347,               
          349-350, 21 USPQ2d 1941, 1943 (Fed. Cir. 1992):                              
                    The question of "structural                                        
                    similarity" in chemical patent cases has                           
                    generated a body of patent law unto                                
                    itself.  [footnote omitted] Particular                             
                    types or categories of structural                                  
                    similarity without more have, in past                              
                    cases, given rise to prima facie                                   
                    obviousness; see e.g., In re Dillon, 919                           
                    F.2d 688, 692-94, 16 USPQ2d 1897, 1900-                            
                    02 (Fed. Cir. 1990) (tri-orthoesters and                           
                    tetra-orthoesters), cert. denied,                                  
                    _____U.S._____, 111 S.Ct. 1682 (1991);                             
                    In re May, 574 F.2d 1082, 197 USPQ 601                             
                    (CCPA 1978) (stereoisomers); In re                                 
                    Wilder, 563 F.2d 457, 195 USPQ 426 (CCPA                           
                    1977)(adjacent homologs and structural                             
                    isomers); In re Hoch, 428 F.2d 1341, 166                           
                    USPQ 406 (CCPA 1970)(acid and ethyl                                
                    ester).                                                            

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