Ex parte COTTER et al. - Page 6




          Appeal No. 93-4191                                                          
          Application 07/831,627                                                      



          appears that some of the patients described by Cotter ‘807,                 
          might be within the breadth of the claims on appeal.  However,              
          the burden is on the examiner, and not this merits panel, to                
          make such findings.  In the event that the examiner does                    
          determine that the patients described by Cotter ‘807, or any                
          other prior art reference, are encompassed by the claims, he                
          must clearly state, on the record, the factual basis for any                
          such findings and provide the appellants with a fair                        
          opportunity to respond.                                                     
               Alternatively, the examiner might consider whether the                 
          specification would have enabled one skilled in the art to                  
          “make and use” the claimed method as required by 35 U.S.C. §                
          112, first paragraph.  The examiner should consider whether                 
          the specifi-cation would have enabled one skilled in the art                
          to determine which patients are encompassed by the claims in                
          the first instance.  That is, the examiner might consider                   
          whether the teachings of the specification would have enabled               
          those skilled in the art, to identify those patients in which               
          the “gut bacteria flora is modified, reduced, or eliminated so              
          as to impair its ability to provide short chain fatty acids as              

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