Ex parte FLYNN et al. - Page 7




          Appeal No. 94-3351                                                          
          Application 07/919,679                                                      


          basis to support the contention that the cited prior art                    
          compounds are structurally similar to the instantly claimed                 
          compounds.  However, statements by the examiner that the claimed            
          serotonergic agents act as 5-HT  antagonists or agonist ?are not            
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          germane to any issue at hand? (Answer, page 8) and the statement            
          that the methods of using the claimed compounds (the utility of a           
          compound is based on its properties) are not under consideration            
          (Answer, page 5) are inconsistent with legal theories of                    
          structural obviousness.  In this regard, we point out to the                
          examiner that an obviousness rejection based on similarity in               
          chemical structure and function entails the motivation of one               
          skilled in the art to make a claimed compound in the expectation            
          that compounds similar in structure will have similar properties.           
          In re Gyurik, 596 F.2d 1012, 1018, 201 USPQ 552, 557 (CCPA 1979);           
          In re May, 574 F.2d 1082, 1094, 197 USPQ 601, 611 (CCPA 1978); In           
          re Hoch, 428 F.2d 1341, 1344, 166 USPQ 406, 409 (CCPA 1970).                
          Thus, the expectation that compounds similar in structure will              
          have similar properties leads one to the conclusion that the                
          compounds will have similar utilities.                                      
               In the case before us, the relied upon prior art references            
          to Watts and King describe their compounds as having multiple               
          identical utilities (see Watts at column 4, lines 47 through 56             

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