Ex parte LILJA et al. - Page 5




          Appeal No. 95-0635                                                          
          Application 07/768,255                                                      


          above-quoted limitations.  Accordingly, we reverse the rejection            
          of claim 8 under 35 U.S.C. § 103 as unpatentable over Lilja.                
               Independent method claims 1 and 12 recite a reagent                    
          containing more than conventional agents used in the glucose                
          dehydrogenase method for determining the glucose content of                 
          blood.  Each of those claims additionally requires a "hemolyzing            
          agent" in the reagent.  Furthermore, claim 1 recites the steps of           
          (1) "performing an absorption measurement at said wavelength                
          range [above 650 nm] directly on the sample in the cuvette;" and            
          (2) "further conducting a secondary absorption measurement to               
          compensate for background interference in a wavelength range                
          above 700 nm."  By the same token, claim 12 recites the steps of            
          (1) "determining by transmission photometry the concentration               
          change of the dye at a wavelength that is in an absorption range            
          above 650 nm., the dye being selected so that the dye                       
          concentration change takes place at least in a wavelength range             
          above 650 nm. which is outside the absorption range of the blood            
          hemoglobin;" and (2) "further conducting a secondary absorption             
          measurement to compensate for background interference in a                  
          wavelength range above 700 nm."                                             
               Manifestly, the examiner has not established a prima facie             
          case of obviousness of claims containing those limitations.  We             
          have carefully reviewed the examiner's discussion of Pierre,                
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