Ex parte CACECI et al. - Page 11




          Appeal No. 95-2041                                                          
          Application 07/814,220                                                      


          plasmid?  Does the claim include bacterial cultures other than              
          E. coli?  It is not ascertainable which cells, beyond the                   
          cells in the culture held at the ATCC, are within the metes                 
          and bounds of claim 21.                                                     


          3."an amino acid sequence defined by blocks...of Figure 4"                  
               Claims 43-47 refer to the blocks of Figure 4.  Claims 43-              
          46 commonly recite: "A synthetic DNA sequence ... comprising a              
          sequence of nucleotides coding for a protein which has an                   
          amino acid sequence defined by blocks ... of Figure 4."  The                
          only variation in these four claims is that a specific segment              
          of "blocks" from Figure 4 is recited in each one of claims 43-              
          46.  Claim 47 recites that the claimed DNA encodes "a protein               
          which has an amino acid sequence with greater than five of the              
          eight blocks shown in Figure 4."  The specification refers to               
          the blocks of Figure 4 at page 10, lines 4-16.  The blocks are              
          indicated in Figure 4 by two-directional arrows.  Blocks 1-8                
          are contiguous in Figure 4.  The specification also                         
          contemplates adding segments which are 11 amino acids in                    
          length at the PST1 site shown in block 7 of Figure 4.  Such an              
          addition would result in a non-contiguous association of                    
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