Ex parte CACECI et al. - Page 16




          Appeal No. 95-2041                                                          
          Application 07/814,220                                                      


          not teach lengthening the polypeptide by adding more than                   
          three repeats.  The genes and hosts of claims 17-20, encode                 
          and produce, respectively, polypeptides which contain the                   
          eight specified 11-amino acid sequence "repeats" of Figure 4.               
          Polypeptides of this length with this number of repeats are                 
          neither taught by nor reasonably suggested by the teachings of              
          Chakrabartty.  Nor is a finding that the limiting factor in                 
          antifreeze activity is the "number of ice contact points"                   
          reasonably supported by the Chakrabartty and Scott teachings.               
          These references note the significance of the number of ice                 
          contact points, but they do not lessen the significance of                  
          other factors, including the known number of contiguous                     
          repeats in known antifreeze polypeptides.                                   
               We disagree with the statement in the above-quoted                     
          section of the Examiner's Answer (page 14, 7-9) which reads                 
          "(note the same conclusion was admitted by appellants from a                
          review of Chakrabartty (19) and Scott, see page 12 last                     
          paragraph, ending on page 13 of the specification)."  The                   
          cited section of the specification is not an admission of a                 
          "conclusion...from a review of Chakrabartty and Scott."                     
          Rather, the section of pages 12 and 13 of the specification to              
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