Ex parte HUNG et al. - Page 6




          Appeal No. 96-0008                                                          
          Application 08/243,428                                                      


               immediately obtain desired results, make certain                       
               experiments and adaptations, within the skill of the                   
               competent worker.  The failures of experimenters who                   
               have no interest in succeeding should not be                           
               accorded great weight.                                                 
               Upon reviewing appellants' evidence of non-enablement,                 
          and the examiner's analysis thereof, we find that appellants'               
          evidence is of sufficient weight to effectively shift to the                
          examiner the burden of demonstrating that one of ordinary                   
          skill in the art would have been able to make the presently                 
          claimed compounds at the time of filing the grandparent                     
          application.  Since the examiner has not come forth with a                  
          convincing line of reasoning based on scientific evidence that              
          refutes appellants'                                                         
          evidence, we find that appellants have rebutted the                         
          presumption of validity attached to the Ohmori patents.  See                
          Hoeksema at 158 USPQ 601.                                                   


               Appellants rely upon the Moore article and the                         
          publication of Chen et al. and Gorbunova, as well as the Hung               
          declaration, as evidence that the reaction between the                      
          perhalogenated alkyl iodide and the allyl alcohol disclosed by              
          the Ohmori patent (see Ohmori I at col. 3, lines 60-65) does                
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