Ex parte HUNG et al. - Page 7




          Appeal No. 96-0008                                                          
          Application 08/243,428                                                      


          not yield the halohydryn taught by Ohmori but, rather, a                    
          primary alcohol with the iodine substituent on the carbon                   
          adjacent the terminal carbon.  In our view, appellants' have                
          produced convincing evidence that the reaction scheme of                    
          Ohmori does not produce the depicted inter-mediate prior to                 
          forming the epoxide.  However, the question remains, unasked                
          by the examiner, whether the error attributed to Ohmori's                   
          reaction scheme is relevant to the ultimate epoxide produced.               
          Appellants have produced no evidence that even if the                       
          intermediate of Ohmori's reaction scheme is a primary alcohol,              
          the epoxidizing  and dehalogenation steps disclosed by Ohmori               
          would not produce the described epoxide compound that is                    
          homologous to the claimed compounds .                                       
               In our view, the compelling evidence for non-enablement                
          is found in the declarations of Krespan and King.  Appellants               
          present Dr. Krespan as "a nationally and internationally                    
          renowned                                                                    




          scientist in the field of organofluorine chemistry," (page 6                
          of brief) and his credentials as an expert in the relevant art              
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