Ex parte CHAMBERLIN et al. - Page 7




          Appeal No. 96-0009                                                          
          Application 08/104,417                                                      


          Marzocchi, 439 F.2d 220, 223, 169 USPQ 367, 369 (CCPA 1971):                
                    [A] specification disclosure which contains a                     
               teaching of the manner and process of making and                       
               using the invention in terms which correspond in                       
               scope to those used in describing and defining the                     
               subject matter sought to be patented must be taken                     
               as in compliance with the enabling requirement of                      
               the first paragraph of §112 unless there is reason                     
               to doubt the objective truth of the statements                         
               contained therein which must be relied on for                          
               enabling support.                                                      
               When making a rejection under 35 U.S.C. § 101, an                      
          examiner must do more than merely question operability.  In re              
          Gaubert, 524 F.2d 1222, 1224-25, 187 USPQ 664, 666 (CCPA                    
          1975).  The examiner “must set forth factual reasons which                  
          would lead one skilled in the art to question the objective                 
          truth of the statement of operability” (id.).                               


               In the present case, the examiner states that appellants               
          claim a mechanism of chemical reactions within the body which               
          are speculative and that appellants’ method for inhibiting                  
          transport of a neurotransmitter away from a synapse is on its               
          face unbelievable (answer, page 4), but the examiner provides               
          no factual basis for these assertions.                                      
               The examiner argues that appellants have not established               

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