Ex parte ORLOWSKI et al. - Page 4




             Appeal No. 1995-4370                                                                                    
             Application 07/401,432                                                                                  


                    The references relied on by the examiner are:                                                    
             Brugger et al. (Brugger)                  3,798,203                  Mar. 19, 1974                      
             Riniker et al. Riniker)                   3,910,872                  Oct.   7, 1975                     
             Sakakibara et al. (Sakakibara)            4,086,221                  Apr. 25, 1978                      
             Orlowski et al. (Orlowski `386)           4,622,386                  Nov. 11, 1986                      
             Orlowski et al. (Orlowski `728)           4,746,728                  May 24, 1988                       
             Swiss (Rittel I)                          PN 550,774                 June 28, 1974                      
             Eur. Pat. App. (Fujii)                    0 330 241                  Aug. 30, 1989                      
             Rittel et al. (Rittel II), Helvetica Chimica Acta, 104. “Thyrocalcitonin III. Die Synthese des " -      
             Thyrocalcitonins,” Vol. 51, pp. 924-28 (1968).                                                          
                    Claims 29, 30, 86 and 87 stand rejected under 35 U.S.C. § 103.  As evidence                      
             of obviousness, the examiner relies upon Brugger, Riniker, Orlowski I, Sakakibara,                      
             Orlowski II, Rittel I, Rittel II and Fujii.  We reverse.                                                
                                                   DISCUSSION                                                        
                    In deciding patentability issues under 35 U.S.C. § 103, the court observed in                    
             Panduit Corp. v. Dennison Mfg. Co., 810 F.2d 1561, 1567-68, 1 USPQ2d 1593, 1597                         
             (Fed. Cir.), cert. denied, 481 U.S. 1052 (1987) “[a]nalysis begins with a key legal question            
             -- what is the invention claimed?” since “[c]laim interpretation . . . will normally                    
             control the remainder of the decisional process.”  In the present case, each of the claims              
             on appeal requires a calcitonin peptide analog with a defined amino acid sequence and                   
             an amide bridge with a specific structure.                                                              




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