Ex parte BRENNER et al. - Page 8




          Appeal No. 98-1012                                                          
          Serial No. 08/117,342                                                       




          Kradolfer as a reference in the ' 103 rejections and raising a new          
          rejection under the enablement requirement of 35 U.S.C. ' 112:              

               ASince Applicants have shown that this particular                      
               antibiotic will destroy by lysis the very bacteria which               
               the instant medium is used to detect, the specification                
               is deemed non-enabling. Applicants have not shown how the              
               antibiotic cefsulodin, which lyses coliform bacteria, may              
               be used in a medium for detection of coliform bacteria@                
               (second supplemental examiner=s answer, paper no. 48.5,                
               p. 2).                                                                 


               Thereafter a debate ensued, with appellants arguing that               
          the data and methodology described in the specification are                 
          satisfactory to teach one how to make and use the claimed                   
          medium, and the examiner arguing, for example, that there are               
          no claim limitations or discussion in the specification                     
          regarding the use of Cefsulodin at a particular concentration               
          such that it will perform as appellants describe; namely,                   
          suppressing non-coliform but not coliform bacteria (third                   
          reply brief, paper no. 49, p. 2; examiner=s answer, paper no.               
          50, p. 2; fourth reply brief, paper no. 51, p. 2; supplemental              




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