Ex parte KWON et al. - Page 7




               Appeal No. 1996-2208                                                                                                    
               Application No. 08/180,194                                                                                              


                       [T]he combined teachings of the references in conjunction with the admitted                                     
                       state of the prior art . . . reasonably teach to one of ordinary skill in the art that                          
                       a variety of protein products in need of debittering would reasonably be                                        
                       expected by one of ordinary skill in the art at the time the claimed invention                                  
                       was made to be debittered successfully by treatment with L. helveticus at                                       
                       least at temperatures up to and including 53EC, which is within the required                                    
                       range.  (Supplemental Examiner’s Answer, page 5).                                                               

                       We disagree with the examiner’s conclusions.  While one might recognize from                                    
               Bergey’s Manual that L. helveticus survives at temperatures up to 53EC, and from Parker                                 
               that bacterial extracts in general can be used over a wide temperature range, these facts                               
               alone do not provide a reason, suggestion or motivation to modify the incubation                                        
               temperature of the debittering processes disclosed by Bartels I and II.  As stated in Pro-                              
               Mold & Tool Co. v. Great Lakes Plastics, Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626,                                      
               1629 (Fed. Cir. 1996) (citation omitted), “It is well-established that before a conclusion of                           
               obviousness may be made based on a combination of references, there must have been a                                    
               reason, suggestion, or motivation to lead an inventor to combine those references.”                                     
                       We have no doubt that the prior art could be modified in a manner consistent with                               
               appellants’ specification and claims, but the fact that the prior art could be so modified                              
               would not have made the modification obvious unless the prior art suggested its                                         
               desirability.  In re Gordon, 733 F.2d 900, 902, 221 USPQ 1125, 1127 (Fed. Cir. 1984).                                   
               Here we find no reason or suggestion stemming from the prior art which would have led a                                 
               person having ordinary skill to the claimed method.  In our judgment, the only reason or                                

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