Ex parte MATSON - Page 14




              Appeal No. 1996-3409                                                                                       
              Application No. 08/092,543                                                                                 


              serial no. 08/105,482 (‘482).  The present claims are directed to “diagnosis,” while the                   
              claims of the ‘482 application are directed to “screening.”  The examiner sets forth the                   
              obviousness relationship between these sets of claims, and provides tenable reasoning                      
              (Examiner’s Answer, paragraph bridging pages 11 and 12).  Appellant does not counter                       
              the examiner’s reasoning, arguing only that the limitations “diagnosing disorders in a test                
              individual,” “fluid samples,” and “predetermined molecular constituents” are not found                     
              verbatim in claim 1 of the ‘482 application and, therefore, that the instant claims “would not             
              have been anticipated or rendered obvious by claims 1-20 of the ‘482 application.”  See                    
              page 27 of the Brief.  This general argument does not controvert the examiner’s position                   
              with a reasonable degree of specificity.  Accordingly, we affirm the provisional rejection of              
              claims 1 through 20 under the doctrine of obviousness-type double patenting.                               
                     Claims 1, 2 and 10 stand rejected as unpatentable over claims 1 through 4 of U.S.                   
              Patent No. 4,863,873, under the doctrine of obviousness-type double patenting;                             
              claims 1 through 5 and 7 through 10 stand rejected as unpatentable over claims 1, 4                        
              through 8, 10, 12 through 16, 18, 19, 22 and 23 of U.S. Patent No. 5,104,639, on the same                  
              ground.  None of the patented claims recites comparison with a frequency distribution                      
              database, nor is that limitation adequately addressed in either rejection.                                 






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