Ex parte DOW - Page 4




              Appeal No. 1997-1856                                                                                      
              Application 08/142,284                                                                                    

                     All in all, we believe that the specification imparts ample information enabling any               
              person skilled in the art to use the claimed compounds throughout their scope without                     
              undue experimentation.  Therefore, we disagree with the examiner's conclusion that the                    
              specification does not satisfy the “how to use” requirement of 35 U.S.C. § 112, first                     
              paragraph.                                                                                                
                     We have carefully reviewed the Examiner's Answer (Paper No. 16) and                                
              Supplemental Answer (Paper No. 18).  In our judgment, however, the examiner does not                      
              adequately explain why she doubts the truth or accuracy of any statement in appellant's                   
              supporting disclosure.  Nor does the examiner back up assertions of her own with                          
              acceptable evidence or reasoning inconsistent with the contested statement.  See In re                    
              Marzocchi, 439 F.2d 220, 223-24, 169 USPQ 367, 369-70 (CCPA 1971).  In this regard,                       
              we find that the examiner's reliance on Kruse and Levitzki is misplaced.  Those references                
              relate to compounds structurally distinct from and not analogous to the instantly claimed                 
              compounds.  In our judgment, therefore, the discussion of tyrosine kinase inhibiting activity             
              in Kruse or Levitzki does not constitute reason to doubt the objective truth of statements in             
              the specification which are relied on by appellant for enabling support.  In re Marzocchi,                
              439 F.2d at 223, 169 USPQ at 369 (CCPA 1971).                                                             
                     To the extent that the examiner would find working examples of “how to use” the                    
              claimed compounds desirable, we agree.  As the court cautioned in In re Strahilevitz,                     



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