Ex parte KOSLEY JR. et al. - Page 3




          Appeal No. 1997-2182                                                        
          Application 08/137,443                                                      
















               wherein                                                                
               R  is hydrogen, (C -C )alkylcarbonyl,1               1  I2                                                 
               (C -C )alkoxycarbonyl, mono(C -C )alkylaminocarbonyl,1 I2                       1 12                                      
               or di(C -C )alkylaminocarbonyl;                                        
                     1  12                                                            
               R  is mono(C -C )alkylaminocarbonyloxy,2         1  I8                                                       
               di(C -C )alkylaminocarbonyloxy, or                                     
                  1  8                                                                
          aryl(C -C )alkylaminocarbonyloxy;                                           
                1 4                                                                   
               R  is hydrogen or halo; or a pharmaceutically3                                                                     
               acceptable acid addition salt thereof.                                 

               Claim 21. A pharmaceutical composition which                           
               comprises a pharmaceutically acceptable carrier and                    
               an acetylcholinesterase inhibiting amount of the                       
               compound of Claim 1.                                                   
                                                                                     
                                                                                     
               Claim 22. A method of treating memory dysfunction                      
               characterized by decreased cholinergic function                        
               which comprises administering to a mammal an                           

                                          3                                           





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