Ex parte KOSLEY JR. et al. - Page 7




          Appeal No. 1997-2182                                                        
          Application 08/137,443                                                      
          limited to "treating" memory dysfunction characterized by                   
          decreased cholinergic function.                                             
               The method requires administering to a mammal with memory              
          dysfunction characterized by decreased cholinergic function an              
          amount of the compound of claim 1 sufficient to inhibit the                 
          formation in the mammal of the enzyme AchE.  As a "comprising"              
          claim the method does not exclude any other step or                         
          ingredient, including steps or ingredients disclosed but not                
          claimed and even steps or ingredients neither disclosed or                  
          even contemplated.                                                          
                       THE "HOW TO USE" REJECTION UNDER § 112                         
               As we have noted above, the examiner, on page 1 of his                 
          Answer, has dropped the rejection of claims 1 through 22 under              
          35 U.S.C. § 101.  Accordingly, the only issue presented for                 
          our consideration is the rejection of claims 1 through 22                   
          under 35 U.S.C. § 112, first paragraph.                                     
               The examiner's rejection of the claims as being based on               
          a specification which fails to adequately teach "how to use"                
          the claimed invention is a rejection under the so-called                    
          "enablement" requirement of the first paragraph of 35 U.S.C. §              
          112.  It is incumbent upon the examiner in rejecting claims                 
          under the first paragraph of 35 U.S.C. § 112, to establish a                
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