Ex parte CHAPMAN et al. - Page 7




             Appeal No. 1997-2271                                                                                 
             Application 08/588,969                                                                               


             1531 (Fed. Cir. 1988).  “Both the suggestion and the                                                 
             expectation of success must be founded in the prior art, not                                         
             in the applicant’s disclosure.”  Id.  The mere fact that the                                         
             prior art could be modified as proposed by the examiner is not                                       
             sufficient to establish a prima facie case of obviousness.                                           
             See In re Fritch, 972 F.2d 1260, 1266, 23 USPQ2d 1780, 1783                                          
             (Fed. Cir. 1992).  The examiner must explain why the prior art                                       
             would have suggested to one of ordinary skill in the art the                                         
             desirability of the modification.  See Fritch, 972 F.2d at                                           
             1266, 23 USPQ2d at 1783-84.                                                                          





                    The examiner argues that one of ordinary skill in the art                                     
             would have had a reasonable expectation of success if the                                            
             teachings of the references were combined as proposed by the                                         
             examiner, but has not explained why the references would have                                        
             fairly suggested, to such a person, the desirability of the                                          
             proposed modification.  The examiner argues that both an                                             
             alkoxy group and a hydroxyl group at the 2-position of a                                             


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