Ex parte ITO et al. - Page 19




          Appeal No. 1998-2836                                                        
          Application No. 08/453,211                                                  


          550 F.2d 656, 660, 193 USPQ 12, 16 (CCPA 1977).  Moreover,                  
          artisans must be presumed to know something about the art                   
          apart from what the references disclose (see In re Jacoby, 309              
          F.2d 513, 516, 135 USPQ 317, 319 (CCPA 1962)) and the                       
          conclusion of obviousness may be made from "common knowledge                
          and common sense" of the person of ordinary skill in the art                
          (see In re Bozek, supra).  It was known in the art prior to                 
          the appellants’ invention that HAp is a main inorganic                      
          component of bone (see Oonishi at col. 1, ll. 54-55 and the                 
          definition of “hydroxyapatite” in The American Heritage                     
          Dictionary of the English Language, supra).  Therefore, we                  
          conclude that the artisan would have understood that calcium                
          phosphate derived from powdered bone is mainly HAp and that                 
          its use in the composition of Ito would have been an obvious                
          alternative to synthetic HAp.                                               
               Finally, the appellants argue (main brief, pp. 12-13)                  
          that Oonishi fails to provide any motivation for producing a                
          hardenable material comprising bone powder.  We are not                     
          persuaded by this argument because a teaching of equivalency                
          in the prior art is itself enough to support a rejection under              
          35 U.S.C.                                                                   
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