Ex Parte ALBRECHT et al - Page 8


                    Appeal No. 2001-1431                                                                                                    
                    Application No. 07/968,553                                                                                              

                                                              Other Issues                                                                  
                            We have to wonder whether the closest prior art has been applied in this                                        
                    case.  For example, U.S. Patent 5,369,010 discloses an immunoassay for HLA                                              
                    B27 in which several cell lines, including two cell lines known to express B27 and                                      
                    one known not to express B27, were analyzed by flow cytometry.2  See column                                             
                    8, line 57 to column 9, line 12.  This patent appears highly relevant to the instant                                    
                    claims but has not previously been considered on the record.  Although the                                              
                    ultimate decision on whether the pending claims are patentable rests with the                                           
                    primary examiner, we urge the examiner to thoroughly consider the patentability                                         
                    of the instant claims in view of the ‘010 patent and any other pertinent prior art.  A                                  
                    copy of the ‘010 patent is attached to this opinion.                                                                    



















                                                                                                                                            
                    2 The ‘010 patent issued November 29, 1994, but has an effective filing date of August 16, 1985.                        

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