Ex parte VASSAROTTI - Page 7




          Appeal No. 1998-2581                                                        
          Application No. 08/472,965                                                  


          establishing a prima facie basis to deny patentability rests                
          with the examiner and the examiner, if relying on a theory of               
          inherency, must provide a basis in fact and/or technical                    
          reasoning to reasonably support a determination that the                    
          allegedly inherent characteristic necessarily flows from the                
          teachings of the prior art.  See In re Oelrich, 666 F.2d 578,               
          581, 212 USPQ 323, 326 (CCPA 1981).  Inherency cannot be                    
          established by probabilities or possibilities.  See In re                   
          Robertson, 169 F.3d 743, 745, 49 USPQ2d 1949, 1951 (Fed. Cir.               
          1999).  The examiner has failed to show by fact and/or reasoning            
          that the insertion of the pipette 34 into the aperture 32 of                
          Zipilivan would have necessarily resulted in a gas-tight or                 
          liquid-tight seal with the concentration chamber.  Actually, the            
          examiner has not cited any evidence or reasoning that the                   
          pipette 34 is even inserted into aperture 32 during the                     
          introduction of the liquid sample since Figures 1 and 4 of the              
          reference do not show the pipette 34 in the aperture 32.  Of                
          course, the pipette 34 must be inserted into aperture 32 and go             
          through channel 36 for withdrawal of the concentrated liquid                
          sample (see col. 3, ll. 28-30; 40-46).  Merely because the sizes            

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